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Cover picture: The diagram illustrates the essential role of interactions between extravillous trophoblast cells and NK cells during pregnancy. The left panel shows the nonpregnant endometrium in the secretory phase of the menstrual cycle just before menstruation. The right panel shows the endometrium in the second half of normal pregnancy when the spiral arteries are remodeled to a depth that penetrates the myometrium. The middle panel shows the situation in preeclampsia where the extent and depth of remodeling is less than in normal pregnancy. See related article by Hiby et al., pp. 957-965, and Commentary by Parham, pp. 951-955.
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