Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections
Andrei E. Medvedev, Arnd Lentschat, Douglas B. Kuhns, Jorge C.G. Blanco, Cindy Salkowski, Shuling Zhang, Moshe Arditi, John I. Gallin, and Stefanie N. Vogel
J. Exp. Med. 2003 198: 521-531.
Published online Aug 18 2003, 10.1084/jem.20030701.
[Abstract][Full Text][PDF][Supplemental Material Index]
Prostaglandin D2 Reinforces Th2 Type Inflammatory Responses of Airways to Low-dose Antigen through Bronchial Expression of Macrophage-derived Chemokine
Kyoko Honda, Masafumi Arima, Gang Cheng, Shinsuke Taki, Hirokuni Hirata, Fukiko Eda, Fumiya Fukushima, Bunpei Yamaguchi, Masahiko Hatano, Takeshi Tokuhisa, and Takeshi Fukuda
J. Exp. Med. 2003 198: 533-543.
Published online Aug 18 2003, 10.1084/jem.20022218.
[Abstract][Full Text][PDF]
Brucella Evades Macrophage Killing via VirB-dependent Sustained Interactions with the Endoplasmic Reticulum
Jean Celli, Chantal de Chastellier, Don-Marc Franchini, Javier Pizarro-Cerda, Edgardo Moreno, and Jean-Pierre Gorvel
J. Exp. Med. 2003 198: 545-556.
Published online Aug 18 2003, 10.1084/jem.20030088.
[Abstract][Full Text][PDF]
Identification of PVR (CD155) and Nectin-2 (CD112) as Cell Surface Ligands for the Human DNAM-1 (CD226) Activating Molecule
Cristina Bottino, Roberta Castriconi, Daniela Pende, Paola Rivera, Marina Nanni, Barbara Carnemolla, Claudia Cantoni, Jessica Grassi, Stefania Marcenaro, Nicolas Reymond, Massimo Vitale, Lorenzo Moretta, Marc Lopez, and Alessandro Moretta
J. Exp. Med. 2003 198: 557-567.
Published online Aug 11 2003, 10.1084/jem.20030788.
[Abstract][Full Text][PDF]
Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
Willem W. Overwijk, Marc R. Theoret, Steven E. Finkelstein, Deborah R. Surman, Laurina A. de Jong, Florry A. Vyth-Dreese, Trees A. Dellemijn, Paul A. Antony, Paul J. Spiess, Douglas C. Palmer, David M. Heimann, Christopher A. Klebanoff, Zhiya Yu, Leroy N. Hwang, Lionel Feigenbaum, Ada M. Kruisbeek, Steven A. Rosenberg, and Nicholas P. Restifo
J. Exp. Med. 2003 198: 569-580.
Published online Aug 18 2003, 10.1084/jem.20030590.
[Abstract][Full Text][PDF]
Coupling Between B Cell Receptor and Phospholipase C-2 Is Essential for Mature B Cell Development
Masaki Hikida, Sachiko Johmura, Ari Hashimoto, Mayuko Takezaki, and Tomohiro Kurosaki
J. Exp. Med. 2003 198: 581-589.
Published online Aug 11 2003, 10.1084/jem.20030280.
[Abstract][Full Text][PDF]
The B Cell Receptor Itself Can Activate Complement to Provide the Complement Receptor 1/2 Ligand Required to Enhance B Cell Immune Responses In Vivo
Joerg Rossbacher and Mark J. Shlomchik
J. Exp. Med. 2003 198: 591-602.
Published online Aug 18 2003, 10.1084/jem.20022042.
[Abstract][Full Text][PDF]
Arf6 and Phosphoinositol-4-Phosphate-5-Kinase Activities Permit Bypass of the Rac1 Requirement for ß1 Integrin–mediated Bacterial Uptake
Regulation of Dendritic Cell Migration to the Draining Lymph Node: Impact on T Lymphocyte Traffic and Priming
Alfonso Martín-Fontecha, Silvia Sebastiani, Uta E. Höpken, Mariagrazia Uguccioni, Martin Lipp, Antonio Lanzavecchia, and Federica Sallusto
J. Exp. Med. 2003 198: 615-621.
Published online Aug 18 2003, 10.1084/jem.20030448.
[Abstract][Full Text][PDF][Supplemental Material Index]
Retinoids Regulate Survival and Antigen Presentation by Immature Dendritic Cells
Frédéric Geissmann, Patrick Revy, Nicole Brousse, Yves Lepelletier, Claudia Folli, Anne Durandy, Pierre Chambon, and Michel Dy
J. Exp. Med. 2003 198: 623-634.
Published online Aug 18 2003, 10.1084/jem.20030390.
[Abstract][Full Text][PDF]
129-derived Strains of Mice Are Deficient in DNA Polymerase and Have Normal Immunoglobulin Hypermutation
John P. McDonald, Ekaterina G. Frank, Brian S. Plosky, Igor B. Rogozin, Chikahide Masutani, Fumio Hanaoka, Roger Woodgate, and Patricia J. Gearhart
J. Exp. Med. 2003 198: 635-643.
Published online Aug 18 2003, 10.1084/jem.20030767.
[Abstract][Full Text][PDF]
Brief Definitive Reports:
Impaired Differentiation of Osteoclasts in TREM-2–deficient Individuals
Marina Cella, Cecilia Buonsanti, Carey Strader, Takayuki Kondo, Andrea Salmaggi, and Marco Colonna
J. Exp. Med. 2003 198: 645-651.
Published online Aug 11 2003, 10.1084/jem.20022220.
[Abstract][Full Text][PDF][[Supplemental Material Index]]
A Role of the Fast ATP-gated P2X1 Cation Channel in Thrombosis of Small Arteries In Vivo
Béatrice Hechler, Nadège Lenain, Patrizia Marchese, Catherine Vial, Véronique Heim, Monique Freund, Jean-Pierre Cazenave, Marco Cattaneo, Zaverio M. Ruggeri, Richard Evans, and Christian Gachet
J. Exp. Med. 2003 198: 661-667.
Published online Aug 11 2003, 10.1084/jem.20030144.
[Abstract][Full Text][PDF]
DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features
Juha Paloneva, Jami Mandelin, Anna Kiialainen, Tom Böhling, Johannes Prudlo, Panu Hakola, Matti Haltia, Yrjö T. Konttinen, and Leena Peltonen
J. Exp. Med. 2003 198: 669-675.
Published online Aug 18 2003, 10.1084/jem.20030027.
[Abstract][Full Text][PDF]
Corrections:
Correction
J. Exp. Med. 2003 198: 677.
Published online Aug 18 2003, 10.1084/jem.2003071719871corr.
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2 Is Essential for Mature B Cell Development
and Have Normal Immunoglobulin Hypermutation