The Journal of Experimental Medicine
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Cover Figure


COVER PICTURE: Visualization of isotype switching in the spleen, 4 d after immunization. The image shows antigen-specific, isotype-switched B cells (green) coexisting in an early germinal center (the central area containing red B220+, IgD- cells surrounded by purple B220+, IgD+ naive B cells), the marginal zone (the rim area containing red B220+, IgD- cells), and red pulp (the dark area below the B220+ follicle). See related article by Pape et al., pp. (pages 1677-1687).
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