The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 94, 373-376, Copyright, 1951, by The Rockefeller Institute for Medical Research New York

ARTICLE

CYTOCHEMICAL STUDIES ON THE KIDNEY : I. ROLE OF CELL MULTIPLICATION IN NORMAL GROWTH



N. B. Kurnick M.D.1

1 From the Laboratory for Cell Research, Department of Medicine, Tulane University School of Medicine, New Orleans

Determinations of the desoxyribonucleic acid (DNA) content of the kidneys of growing rats were made on the whole tissues and on isolated nuclei. It was found that the DNA content per nucleus is constant in rats of different weights. The DNA content of the kidneys increased proportionately to their mass over the range studied. It is concluded that increase in mass is primarily due to cell multiplication.

Submitted on July 11, 1951


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