The Journal of Experimental Medicine
BioLegend: Antibody Reagents
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The Journal of Experimental Medicine, Vol 65, 219-231, Copyright, 1937, by The Rockefeller Institute for Medical Research New York

ARTICLE

IMMUNIZATION OF RABBITS TO INFECTIOUS PAPILLOMATOSIS

Richard E. Shope M.D.1

1 From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.

Two intraperitoneal injections of either infectious or non-infectious rabbit papilloma suspensions actively immunize rabbits against papillomatosis. The capacity of the non-infectious suspensions to immunize is considered as evidence that they contain papilloma virus even though none can be demonstrated by the usual infection test.

Submitted on October 20, 1936


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