The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 64, 7-18, Copyright, 1936, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON NATURAL IMMUNITY TO PNEUMOCOCCUS TYPE III : I. THE CAPACITY OF STRAINS OF PNEUMOCOCCUS TYPE III TO GROW AT 41°C. AND THEIR VIRULENCE FOR RABBITS



John F. Enders Ph.D.1 and Morris F. Shaffer Ph.D.1

1 From the Department of Bacteriology and Immunology, The Harvard Medical School, Boston

1. A correlation appears to exist between the failure of certain strains of Pneumococcus Type III to grow at 41°C. and their lack of virulence for rabbits.

2. It is likely that the capacity to grow at 41°C.—an attribute constantly but not exclusively associated with strains of Pneumococcus Type III virulent for rabbits—is a prerequisite, but not the sole factor, in determining their virulence for these animals.

 Submitted on April 15, 1936


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