The Journal of Experimental Medicine, Vol 62, 85-99,
Copyright, 1935, by The Rockefeller Institute for Medical Research New York
EXPERIMENTS ON THE EPIDEMIOLOGY OF PSEUDORABIES
:
I. MODE OF TRANSMISSION OF THE DISEASE IN SWINE AND THEIR POSSIBLE RÔLE IN ITS SPREAD TO CATTLE
Richard E. Shope M.D.1
1 From the Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
Pseudorabies is a very fatal but non-contagious disease in cattle and the common laboratory animals. It is a relatively mild yet highly contagious disease in swine. It has been shown that in swine the nose serves both for the entrance and the exit of the virus. Furthermore, it has been observed that fatal pseudorabies infections in rabbits can be induced merely by bringing their abraded skin into contact with the noses of infected swine. The blood sera of swine on two farms where pseudorabies had occurred among the cattle were found to be capable of neutralizing pseudorabies virus. It is believed that in these instances the swine had a mild and unrecognized pseudorabies infection and transmitted their disease to the cattle with which they were associated, by transfer of the virus on their noses to the abraded skin of the cattle.
Submitted on May 7, 1935
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
