The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 62, 31-37, Copyright, 1935, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE IMMUNOLOGICAL SPECIFICITY OF STAPHYLOCOCCI : III. INTERRELATIONSHIPS OF CELL CONSTITUENTS



L. A. Julianelle Ph.D.1 and C. W. Wieghard 1

1 From the Oscar Johnson Institute, Washington University School of Medicine, St. Louis

1. The carbohydrates derived from Staphylococcus are type specific.

2. The specific carbohydrates fail to induce formation of antibodies in rabbits.

3. Acetylation or adsorption of the carbohydrates on collodion particles does not render them antigenic.

4. The specific carbohydrates may be employed to elicit immediate, type specific, skin reactions in patients with Staphylococcus infection.

5. The protein of Staphylococcus is species specific.

6. The protein is antigenic and stimulates in rabbits species specific antibodies.

7. The protein causes in hypersensitive individuals a species specific, delayed, inflammatory skin reaction.

 Submitted on March 31, 1935


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