The Journal of Experimental Medicine, Vol 60, 503-513,
Copyright, 1934, by The Rockefeller Institute for Medical Research New York
IRREVERSIBLE CHARACTER OF THE LATE CHANGES AFTER HEPATECTOMY
Philip D. McMaster M.D.1 and
D. R. Drury M.D.1
1 From the Laboratories of The Rockefeller Institute for Medical Research
The symptoms of advanced liver insufficiency, in the hepatectomized rabbit, are irreversible. That is to say, cross-transfusions between liverless rabbits and normal ones fail to ameliorate the symptoms of liver deprivation once they are established. The normal rabbits show no symptoms suggesting that toxic substances have accumulated in the blood of the hepatectomized ones.
Submitted on May 30, 1934