The Journal of Experimental Medicine
Cytokines in immune regulation
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The Journal of Experimental Medicine, Vol 60, 149-161, Copyright, 1934, by The Rockefeller Institute for Medical Research New York

ARTICLE

VARYING INFLUENCE OF TUBERCULOUS RABBIT PLASMA ON THE GROWTH OF FIBROBLASTS IN VITRO

Homer F. Swift M.D.1, Johannes K. Moen M.D.1, and Ernst Vaubel M.D.1

1 From the Hospital of The Rockefeller Institute for Medical Research

Plasma obtained from tuberculous rabbits within 3 or 4 months following inoculation with bovine tubercle bacilli exerted a growth-inhibitory influence on transplants of rabbit fibroblasts; while that obtained after the 4th month was growth-stimulating. It is suggested that the growth-inhibitory factor was linked in part with lipoidemia; while the growth-stimulating elements were associated with the period of leucocytosis.

Submitted on May 17, 1934


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