The Journal of Experimental Medicine
MBL International Tel: 800.200.5459 CLICK HERE
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 623K)
Right arrow Alert me when this article is cited
Right arrow Citation Map
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hawkins, W. B.
Right arrow Articles by Wright, A.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Hawkins, W. B.
Right arrow Articles by Wright, A.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 59, 427-439, Copyright, 1934, by The Rockefeller Institute for Medical Research New York

ARTICLE

III. BLOOD PLASMA CHOLESTEROL : FLUCTUATIONS DUE TO LIVER INJURY AND BILE DUCT OBSTRUCTION



William B. Hawkins M.D.1 and Angus Wright M.D.1

1 From the Department of Pathology, The University of Rochester School of Medicine and Dentistry, Rochester, N. Y.

Hypocholesteremia with dissociation of the normal ratio of esterified to total cholesterol is related to chronic liver injury caused by chloroform.

Hypercholesteremia may develop after prolonged biliary obstruction.

The hypercholesteremia of chronic biliary obstruction may be promptly reduced below normal by chloroform poisoning or bile duct infection.

Acute injury of liver due to chloroform anesthesia may cause no change in blood plasma cholesterol.

Absence of bile in the intestine with faulty fat absorption does not cause the development of hypocholesteremia with dissociation of the ester ratio.

Poor food consumption or short periods of fasting may cause no change in blood plasma cholesterol.

Liver cells injured by chloroform may subsequently become resistant to chloroform.

After prolonged biliary obstruction, the liver is apparently more sensitive to small doses of chloroform by mouth.

Analysis of blood plasma cholesterol may have a clinical application in differentiation between simple obstructive and parenchymatous lesions of the liver.

 Submitted on December 27, 1933


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:



  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS