¹ From the Department of Physiology, The Harvard School of Public Health, and the Department of Bacteriology, The Harvard Medical School, Boston

In anesthetized dogs the popliteal lymph node alone, and the popliteal and iliac lymph nodes in series, have been perfused with solutions containing dog erythrocytes and streptococci. The perfusions have been carried out under conditions of lymph flow and pressure within the limits of those occurring in the actively moving dog, or after a severe degree of inflammatory swelling has developed. Figures for filtration are given, with protocols of typical experiments. They indicate that normal lymph nodes possess a high degree of filtering efficiency—an efficiency so great as to make it fairly certain that in a part kept at rest early in an infection, practically no microorganisms would escape the nodes in the line of drainage.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• Gretz, J. E., Norbury, C. C., Anderson, A. O., Proudfoot, A. E.I., Shaw, S. (2000). Lymph-borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex. JEM 192: 1425-1440 [Abstract] [Full Text]  
• Van Wyck, D. B., Lucas, D. O. (1977). Immune Function in Disorders of the Lymph Circulation. VASC ENDOVASCULAR SURG 11: 152-159  
• FOSTER, A. K. Jr. (1938). DISEASE OF THE MESENTERIC LYMPH NODES: ITS RELATION TO APPENDICITIS, GASTRO-INTESTINAL INFECTIONS AND GENERALIZED DISEASES; REPORT OF ONE HUNDRED AND TWENTY-THREE CASES; POSSIBLE ETIOLOGY AND TREATMENT. Arch Surg 36: 28-52 [Abstract]  

Home | Help | Feedback | Subscriptions | Archive | Search

TABLE OF CONTENTS