The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 41, 807-816, Copyright, 1925, by The Rockefeller Institute for Medical Research New York

ARTICLE

EXPERIMENTAL PRODUCTION AND TRANSMISSION OF TAR SARCOMAS IN CHICKENS

James B. Murphy M.D.1 and Karl Landsteiner M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research.

Two spindle cell sarcomas have developed as the result, of injection of coal tar into induced embryomas in chickens. One of these, transplanted to other chickens for eleven generations, is highly invasive in character, and metastasizes freely. Attempts to transmit this neoplasm by a filtrate or desiccate of the tumor have failed of success.

Submitted on April 5, 1925


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