The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 35, 1-6, Copyright, 1922, by The Rockefeller Institute for Medical Research New York

ARTICLE

EXPERIMENTAL STUDIES OF THE NASOPHARYNGEAL SECRETIONS FROM INFLUENZA PATIENTS : VI. IMMUNITY REACTIONS.



Peter K. Olitsky M.D.1 and Frederick L. Gates M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

The experiments described furnish additional evidence of the pathogenic character and the virtual identity of the various strains of the active agent derived from the nasopharyngeal secretions of influenzal patients with which the transmission experiments in rabbits have been carried out.

The active material has been shown to be of antigenic nature, so that rabbits are protected from the effects of a second inoculation. The experiments indicate also the antigenic identity of the various strains of the active agent with each other and with Bacterium pneumosintes.

Finally, the experiments show that the protection may persist for 14 months which is the longest period yet tested.

 Submitted on July 15, 1921


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