The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 108, 283-297, Copyright, 1958, by The Rockefeller Institute

ARTICLE

THE SYNTHESIS OF A TETRADECAPEPTIDE RENIN SUBSTRATE

Leonard T. Skeggs Jr. Ph.D.1, Kenneth E. Lentz Ph.D.1, Joseph R. Kahn M.D.1, and Norman P. Shumway M.D.1

1 From the Department of Medicine and Surgery, Veterans Administration Hospital, and the Department of Pathology, Western Reserve University, Cleveland

A tetradecapeptide renin substrate having a biological activity comparable to the natural product and similar chemical properties has been synthesized by means of the carbobenzyloxyl azide and mixed anhydride methods.

Submitted on May 5, 1958


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