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The Journal of Experimental Medicine, Vol 107, 797-812, Copyright, 1958, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE DIFFERENTIATION OF THREE DISTINCT DESOXYRIBONUCLEASES OF GROUP A STREPTOCOCCI

Lewis W. Wannamaker M.D.1

1 From The Rockefeller Institute for Medical Research

Group A streptococci were found to produce three different desoxyribonucleases, designated here as A, B, and C. These enzymes migrated separately on analysis with starch zone electrophoresis, were immunologically distinct, and showed certain differences in inhibition by citrate and in optimal pH of activity. The relative amount of each enzyme produced was a function of strain variation.

Submitted on January 27, 1958


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